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Bengaluru: Aster Foundation saves baby with rare illness
DTMT Network
Doctors at Bengaluru’s Aster CMI Hospital have given a new lease of life to a 3-month-old Hyderabad-based baby by performing a life saving stem cell procedure (surgery) on him.
The surgery could be possible through a Rs 10 lakh fund raised by Aster Sick Kids Foundation. The average cost of such complex surgeries is around Rs 30-40 lakh. Also, a significant proportion of the Rs. 10 lakh required for post-transplant care was funded by the foundation.
The baby was suffering from Severe Combined Immune Deficiency (SCID), a dreaded disease that is 100% fatal in the absence of definitive treatment. SCID can only be cured with a stem cell transplant.
SCID is a serious form of Primary Immunodeficiency Disease (or PIDs), a genetic disorder where children are born with very weak or defective immune systems. Children with PIDs are prone to develop repeated, unexplainable illnesses and often die at a young age. The underlying condition may often be missed unless evaluated by an immunologist.
At the tender age of just one month, the baby had already developed multiple infections and was suffering from loose motions, abscess on buttocks, cough, rapid breathing and high fever that could not be resolved with antibiotics and was progressively getting worse.
It was found that the baby had a very low lymphocyte count (white blood cells that fight infections) and his T-cells (a type of white cell that is very crucial to fight infections) were absent altogether.
“Upon reviewing the family’s medical background, we discovered that the family had lost their first child at the age of 3 months, likely due to the same disease,” said Dr. Sagar Bhattad, Pediatric Immunologist, Aster CMI Hospital.
“Through a stem cell or bone marrow transplant, we introduce healthy cells into the baby’s system which then start to create fully functional white blood cells that are capable of fighting infections. Such cases are challenging because the baby’s immune system is severely weakened and gives us a very short time frame to conduct the transplant to save the baby’s life,” said Dr. Stalin Ramprakash, Pediatric BMT expert, Aster CMI Hospital.
“There is also a higher risk of mortality when the transplant is done while the child is suffering from active infections. However, once the transplant is done, in most cases the patient is able to make a full recovery and return to normal life,” added Dr Ramprakash.
The baby was treated for one month in the bone marrow transplant unit and discharged once the new white blood cells from the donor stem cells started getting produced (engraftment).
The hospital is also providing free Immunoglobulin infusions every month. The child is now free of infections, has put on weight and is set for a healthy future.
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