ICMR develops cheapest POC testing for severe Hemophilia A

ICMR develops cheapest
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NEW DELHI : The ICMR-National Institute of Immunohematology, Mumbai, has developed a cost-effective point of care (POC) rapid diagnostic test for severe Hemophilia A & VWD.

This is the first in the world POC test for specific diagnosis of any common bleeding disorder. Working cost of these kits is less than Rs. 50, in comparison to existing conventional test for the diseases that cost around Rs. 4000 to Rs. 10000.

Diagnosis of VWD requires a battery of expensive investigations. Patients with severe Hemophilia A or VWD can have life threatening spontaneous or post-traumatic bleeding like brain hemorrhage and gastrointestinal bleeding or they may have bleeding into joints or superficial bleeding from the nose or gums.

In an Emergency Medical setting, it is important to have a quick diagnosis of bleeding disorders for treatment with specific products like the blood components or commercially available factor concentrates which are exorbitantly expensive.

This rapid test kit can be used for the diagnosis of undiagnosed patients/ menorrhagia cases/ post-partum hemorrhage (PPH), gynecological complications with bleeding history, recovery of factors in the transfused Hemophilia A patients and also for differential diagnosis of Hemophilia A and VWD.

Since it does not require any expertise or infrastructure, this can easily access any level of health care system including primary health care centers.

The diagnosis can be done within 30 minutes of blood sample collection. The bands are visually detected within 10 minutes of sample application. The kit is composed of special paper membranes which have different components attached on it for the detection of target molecules.


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