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Dabigatran Etexilate- treatment, side effects and drug interactions

Look for Drugs and Conditions

Dabigatran Etexilate

Dabigatran Etexilate

Dabigatran is an anticoagulant that works by the clotting protein thrombin. It is used to prevent blood clots from forming because of a certain irregular heart rhythm (atrial fibrillation). Preventing these blood clots helps to reduce the risk of a stroke.

Indications

To reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation.


Dosage

Oral; 150mg twice daily, dose depends on renal clearance


Contra-Indications

Active bleeding Hypersensitivity.


Special Precautions

Paediatric: Safety not established. Pregnancy: Category C; Use if risk to fetus outweighs benefits. Lactation: Not known if secreted in milk. Elderly: The risk of stroke and bleeding inreases with age, but the risk-benefit profile is favorable in all age groups.


Side Effects

Bleeding (may be intracaranial), allergic reaction.


Drug Interactions

Anticoagulant, rifampicin, verapamil, amiodarone, quinidine, and clarithromycin


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