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DOCUSATES (Dioctyl sulfo succinate)

DOCUSATES (Dioctyl sulfo succinate)

It is an anionic detergent, softens the stools by net water accumulation in the intestinal lumen. It emulsifies the colonic contents.

Indications

Habitual geriatric, obstetric & paediatric constipation where laxatives/straining are to be avoided (early pregnancy, recent myocardial infarction, severe hypertension, abdominal hernia, ost-operative cases) Piles fissures & bed ridden patients.


Dosage

50-500 mg daily in divided doses.


Special Precautions

By a detergent action, it can disrupt the mucosal barrier and enhance the absorption of many non-absorbable drugs e.g. liquid paraffin-should not be combined with it. Paediatrics: Dose to be reduced. Pregnancy: Use with caution. Lactation: Use with caution. Elderly: Safe.


Side Effects

Cramps & abdominal pain, nausea. Hepatotoxicity is feared on prolonged use.


Drug Interactions

Enhances absorption of laxatives.


Other Brands With Same Generic
Brand Name Manufactured by
CELLUBRIL ASTRA ZENECA PHARMA INDIA LTD.
LAXICON STADMED PRIVATE LIMITED
Other Combination Brands
Brand Name Manufactured by
Irocal PN FINECURE PHARMA
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