Empagliflozin with Linagliptin

Empagliflozin with Linagliptin is a combination medication used in the treatment of type 2 diabetes mellitus. It combines two different classes of antidiabetic drugs, namely empagliflozin and linagliptin, to improve glycemic control in patients with diabetes. Here is a detailed overview of the key aspects of this medication: Empagliflozin is a sodium-glucose co-transporter-2 (SGLT2) inhibitor, while Linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. The combination of these two drugs works by targeting different mechanisms in the body to reduce blood glucose levels in patients with type 2 diabetes.

Indications

Empagliflozin with Linagliptin is indicated for the management of type 2 diabetes mellitus in adults. It is typically prescribed when diet and exercise alone do not provide adequate glycemic control.

Dosage

The dosage of Empagliflozin with Linagliptin may vary based on individual patient factors. It is important to follow the prescribed dosage provided by the healthcare professional.

Contra-Indications

This medication is contraindicated in patients with a known hypersensitivity to empagliflozin, linagliptin, or any of the excipients. It should also be avoided in patients with severe renal impairment, end-stage renal disease, or a history of serious hypersensitivity reactions to these drugs.

Special Precautions

Special precautions should be taken in patients with a history of urinary tract infections, genital infections, or volume depletion. Monitoring renal function regularly is important, and the medication may need to be discontinued if acute kidney injury occurs.

Side Effects

Common side effects may include urinary tract infections, increased urination, nasopharyngitis, and upper respiratory tract infections. Serious side effects may include hypoglycemia when used in combination with insulin or sulfonylureas, ketoacidosis, and acute kidney injury.

Drug Interactions

Empagliflozin with Linagliptin may interact with certain medications, including diuretics, antihypertensive drugs, and medications that affect renal function. It is important to inform the healthcare provider about all medications being taken, including over-the-counter drugs and herbal supplements.