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Flunarizine with Propranolol

Flunarizine with Propranolol

Flunarizine with Propranolol is a combination medication that contains flunarizine, a calcium channel blocker, and propranolol, a non-selective beta-blocker. This combination is designed to provide synergistic effects in the management of certain medical conditions.

Indications

Flunarizine with Propranolol is indicated for the prophylaxis of migraine headaches, particularly those with associated symptoms such as aura. It is also used in the management of vestibular disorders, including vertigo and balance disorders.


Dosage

Dosage may vary based on individual patient characteristics and the specific condition being treated. It is important to follow the prescribed dosage and administration instructions provided by the healthcare provider.


Contra-Indications

Flunarizine with Propranolol is contraindicated in patients with a history of hypersensitivity to either flunarizine or propranolol. It is also contraindicated in individuals with certain cardiovascular conditions, severe respiratory diseases, or hepatic impairment.


Special Precautions

Special precautions should be taken in patients with pre-existing cardiovascular conditions, respiratory disorders, or hepatic dysfunction. Caution is advised in individuals with a history of depression, as propranolol may exacerbate this condition.


Side Effects

Common side effects may include fatigue, dizziness, nausea, and mild gastrointestinal discomfort. Serious side effects such as bradycardia, hypotension, or exacerbation of respiratory conditions may occur and require immediate medical attention.


Drug Interactions

Flunarizine with Propranolol may interact with other medications, including antihypertensives, antiarrhythmics, and medications metabolized by the CYP2D6 enzyme. Careful monitoring and dose adjustments may be necessary when co-administered with certain drugs.


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