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FLUTAMIDE

FLUTAMIDE



Indications

Advanced prostatic cancer.


Dosage

250 mg three times daily.


Contra-Indications

History of thrombo-embolic disorders. Severe chronic depression.


Special Precautions

Monitor liver function tests periodically. Fluid retention can occur i patients with cardiac disease. Paediatrics: Not recommended. Pregnancy: Safety not established. Lactation: Safety not established. Elderly: No special problem.


Side Effects

Nausea, vomiting, diarrhoea, stomatis, shedding of mucosa. Gynaecomastia, breast tenderness, glactorrhoea, insomnia, C.N.S. disturbances.


Drug Interactions

Warfarin increases prothrombin time.


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