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INSULINS

INSULINS

Secretion of insulin from B cells of pancreas, which has a overall effects to favour storage of fuel. Insulin also facilitates glucose transport across cell membrane & glycogen synthesis from glucose in liver, muscle and fat by stimulating the enzyme glycogen synthetase. It inhibits gluconeogenesis (fromprotein) in liver and lipolysis in adipose tissue and favours triglyceride synthesis. In diabetes there is under utilization and over production of glucose leading to hyper glycaemia & glycosuria. During diabetes increased amounts of fat are broken down due to unchecked action of lipolytic hormones resulting in production of ketone bodies & ketonemia or ketonuria. Various insulin preparations containing bovine, porcine or human insulin are available whic constitute the short acting, intermediate & long acting categories.

Indications

Actrapid is for insulin requiring diabetes mellitus. It is particularly suitable: when intense and rapid insulin action is required. In intensified insulin treatment, based on multiple daily injections (basal-bolus therapy) or continuous insulin infusion in treating diabetic emergencies, such as diabetic coma/precoma for diabetics in need of i.v. insulin infusion (e.g. during surgery)


Dosage

Dose to be adjusted as per individual requirements.


Contra-Indications

Hypoglycaemia & insulinoma.


Special Precautions

are same as that of Actraphane.


Other Brands With Same Generic
Brand Name Manufactured by
HUMASTRAD VOLTA (CADILA)
RAPIDICA NICHOLAS PIRAMAL INDIA
Other Combination Brands
Brand Name Manufactured by
PRODICA NICHOLAS PIRAMAL INDIA
RAPIMIX NICHOLAS PIRAMAL INDIA
ZINULIN NICHOLAS PIRAMAL INDIA
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