Lamivudine with Zidovudine and Nevirapine

This combination medication contains Lamivudine, Zidovudine, and Nevirapine, which are antiretroviral drugs used to treat HIV (human immunodeficiency virus) infection. Lamivudine and Zidovudine belong to the nucleoside reverse transcriptase inhibitor (NRTI) class, while Nevirapine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). This triple therapy helps control the progression of HIV by inhibiting viral replication.

Indications

Treatment of HIV-1 infection in adults and pediatric patients. Reduction of the risk of HIV-1 transmission from mother to child during childbirth.

Dosage

Dosage may vary based on individual patient factors. Always follow the prescribed dosage and administration guidelines provided by healthcare professionals.

Contra-Indications

Do not use this medication if the patient: -Has a history of hypersensitivity to any of the components. -Is taking medications that may interact negatively with Lamivudine, Zidovudine, or Nevirapine.

Special Precautions

-Monitor liver function regularly. -Evaluate patients for signs of immune reconstitution syndrome. -Use with caution in patients with pre-existing hepatic or renal impairment.

Side Effects

-Common side effects may include nausea, headache, fatigue, and gastrointestinal disturbances. -Severe side effects such as hepatotoxicity and skin reactions may occur. Consult a healthcare professional if adverse reactions persist or worsen.

Drug Interactions

-Inform healthcare providers of all medications, including over-the-counter and herbal supplements. -Possible interactions with other antiretroviral drugs, rifampicin, and certain antifungals.