LIRAGLUTIDE

Indications

As an adjunct to diet and exercise in management of type 2 diabetes mellitus.

Dosage

1.2-1.8 mg once daily subcutaneously, irrespective of meals. Maximum dialy dose : 1.8 mg.

Contra-Indications

In patients with a personal or family history of medullary thyroid carcinoma and in patients with multiple endocrine neoplasia syndrome 2.

Special Precautions

In patients with reanl failure, hepatic impairment and history of pancreatitis.

Side Effects

Nausea, vomiting, diarrhoea, weight gain, pancreatitis, bladder pain, low incidence of hypoglycaemia, formation of anti-liraglutide antibodies,acute tubular necrosis have been recently reported severe allergic reactions may occur.

Drug Interactions

Hormonal contraceptives, bosentan, barbiturates, felbamate, griseofulvin, carbamazapine, phenytoin, rifampicin, topiramate.