Modafinil

It belongs to Amphetamines class. It is a powerful CNS stimulant

Indications

Nacrolepsy Syndrome; Sleepiness due to obstructive sleep Apnea, sleepiness due to shift work sleep disorder.

Dosage

Adult min/max : 200mg/400mg orally once daily in the morning.

Contra-Indications

Left ventricular hypertrophy, mitral valve prolapse, Myocardial ischemia, Acute ST-elevation myocardial infraction, Disease of liver, psychotic disorder, Renal disease, unstable angina pectoris, hypertension. Hypersensitivity to modafinil.

Special Precautions

Pregnancy : Only when necessary. Lactation : May inhibit lactation.

Side Effects

Headache, chills, fever, rhinitis, pharyngitis, backache, dyspepsia, anorexia, nausea, vomiting, diarrhoea, dyspnoea, anxiety, nervousness, depression, dizziness, insomnia, amentia, inpaired cognition, moodchanges, dyskinesia, hypertonia, paresthesia, tremors, amblyopia, cardiac arrhythmias, hypertension, hypotension, vasodilatation of blood vessels, hyperglycemia, polydypsia, xerostomia, dry skin, urinary retention, abnormal liver function tests.

Drug Interactions

Modafinil decreases the effect of steroidal contraceptives.