A PHP Error was encountered

Severity: Warning

Message: fopen(/var/cpanel/php/sessions/ea-php74/ci_sessioncfafd096fb9e0c0dbdf132ae1ee675a8e8d9ad9c): failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 176

Backtrace:

File: /home/drugtodayonline/public_html/application/controllers/Drug_directory.php
Line: 9
Function: __construct

File: /home/drugtodayonline/public_html/index.php
Line: 311
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/cpanel/php/sessions/ea-php74)

Filename: Session/Session.php

Line Number: 143

Backtrace:

File: /home/drugtodayonline/public_html/application/controllers/Drug_directory.php
Line: 9
Function: __construct

File: /home/drugtodayonline/public_html/index.php
Line: 311
Function: require_once

Naltrexone- Drug Interactions, Dosage, Side Effects, indications, Uses and Precautions

Look for Drugs and Conditions

NALTREXONE

NALTREXONE

It is an opioid antagonist. It completely blocks the subjective effects of opioids by competitively binding at opioid receptors. Duration of action is dose related and much longer than that of naloxone.

Indications

Opioid dependence (as an aid to prevent relapse). Adjunctive treatment in chronic alcoholism.


Dosage

Opioid dependence: Patients should be opioid free for atleast 7-10 days. Initiate therapy in specialist clinics only. 25 mg initially, then 50 mg daily; once stabilized, total weekly dose may be divided and given on 3 alternate days of the week. Adjunctive treatment in chronic alcoholism: 50 mg once daily.


Contra-Indications

Patients concurrently dependent on opioids; acute hepatitis or hepatic failure, acute opioid withdrawal; patients on therapeutic opioid analgesics; hypersensitivity.


Special Precautions

Hepatic or renal impairment; LFTs needed before and during treatment. Test for presence of opioid molecules in the body using urine screening or naloxone challenge, if required (patients should be opioid free for atleast 7-10 days prior to initiating naltrexone therapy). Patients are strictly warned against the use of opioids while on naltrexone. Pregnancy and lactation.


Side Effects

Abdominal pain, nausea, vomiting, anxiety, insomnia, lethargy, headache, musculoskeletal pain, anorexia, diarrhea, constipation, increased thirst, sweating and lachrymation, chest pain, irritability, chills, dizziness, sexual dysfunction, rash, liver function abnormalities and reversible idiopathic thrombocytopenia.


Drug Interactions

Excessive opioids can result in acute opioid intoxication; in addition, excessive opiates release histamine resulting in facial swelling, itching and erythema. Concurrent hepatotoxic drugs may increase the risk of hepatic dysfunction.


A PHP Error was encountered

Severity: Warning

Message: mysqli::query(): (HY000/1): Can't create/write to file '/tmp/#sql_3cd_0.MYI' (Errcode: 28 - No space left on device)

Filename: mysqli/mysqli_driver.php

Line Number: 307

Backtrace:

File: /home/drugtodayonline/public_html/application/models/Site_ads_model.php
Line: 118
Function: query

File: /home/drugtodayonline/public_html/application/libraries/Common_lib.php
Line: 318
Function: get_front_ads_data

File: /home/drugtodayonline/public_html/application/views/front/salt_info.php
Line: 165
Function: common_footer_ads

File: /home/drugtodayonline/public_html/application/controllers/Drug_directory.php
Line: 331
Function: view

File: /home/drugtodayonline/public_html/application/controllers/Drug_directory.php
Line: 29
Function: drug_info

File: /home/drugtodayonline/public_html/index.php
Line: 311
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: Cannot modify header information - headers already sent by (output started at /home/drugtodayonline/public_html/system/core/Exceptions.php:271)

Filename: core/Common.php

Line Number: 570

Backtrace:

File: /home/drugtodayonline/public_html/application/models/Site_ads_model.php
Line: 118
Function: query

File: /home/drugtodayonline/public_html/application/libraries/Common_lib.php
Line: 318
Function: get_front_ads_data

File: /home/drugtodayonline/public_html/application/views/front/salt_info.php
Line: 165
Function: common_footer_ads

File: /home/drugtodayonline/public_html/application/controllers/Drug_directory.php
Line: 331
Function: view

File: /home/drugtodayonline/public_html/application/controllers/Drug_directory.php
Line: 29
Function: drug_info

File: /home/drugtodayonline/public_html/index.php
Line: 311
Function: require_once

Database Error

A Database Error Occurred

Error Number: 1

Can't create/write to file '/tmp/#sql_3cd_0.MYI' (Errcode: 28 - No space left on device)

SELECT * FROM `dt_site_ads` WHERE `status` = '1' and `loc` = 'pre_footer_4' ORDER BY RAND() LIMIT 0,1

Filename: models/Site_ads_model.php

Line Number: 118