NICLOSAMIDE

Highly effective drug against cestodes infesting man-Taenia Saginate, T. Solium, Diphyllobothrium latum and Hymenolepiasis nana. as well as thread worm. A saline purgative is given 2 hours after the dose to wash off the worm.

Indications

Taenia saginata. Taenia solium. Diphyllobothrium latum, Hymenolepis nana.

Dosage

Adults and children over 6 yrs: 1gm followed by another dose of 1 gm one hour later. Single dose of 2 gm may also be given. Brisk purgative after 2 hours of last dose recommended. Children:(2-6yrs) 1 gm total dose in 2 divided doses.

Contra-Indications

Hypersensitivity.

Special Precautions

Digestion of the dead segments of injuredT. Solium can be hazardous, as the ova released from them may develop into larvae in the intestine, penetrate its wall and cause visceral cysticercosis, thus a thorough purge is essential: The scolex should be searched in the stools to be sure that the worm will not grow again. Paediatrics: Use with caution. Pregnancy: Use with caution. Lactation: Use with caution. Elderly: Safe.

Side Effects

G.I. upset, pruritus.

Drug Interactions

Alcohol may enhance absorption of the drug.