OESTRADIOL PHENYLPROPIONATE

Oestradiol Phenylpropionate is a synthetic form of the natural female sex hormone estrogen, specifically estradiol. It is commonly used in hormone replacement therapy (HRT) for women experiencing menopausal symptoms or those who have undergone surgical removal of the ovaries. Oestradiol Phenylpropionate is an estradiol ester, meaning it is a modified form of estradiol with a phenylpropionate ester attached. This modification allows for a slower release of the hormone into the bloodstream.

Indications

Hormone Replacement Therapy (HRT): Alleviates menopausal symptoms like hot flashes, vaginal dryness, and mood swings. Postmenopausal Osteoporosis Prevention: Helps maintain bone density in postmenopausal women. Hypogonadism: Treatment for estrogen deficiency conditions.

Dosage

Dosage may vary based on individual patient factors and the specific condition being treated. It is typically administered via intramuscular injection, and the frequency of administration depends on the formulation and the patient's response.

Contra-Indications

Breast Cancer: Contraindicated in patients with a history of breast cancer. Pregnancy: Should not be used during pregnancy due to potential harm to the fetus. Liver Disease: Contraindicated in severe liver dysfunction.

Special Precautions

Cardiovascular Health: Use with caution in patients with a history of cardiovascular disease. Thromboembolic Disorders: Increased risk in patients with a history of thromboembolic disorders. Migraine: May exacerbate migraines in some individuals.

Side Effects

Breast Tenderness: Common side effect. Nausea: Occasional gastrointestinal discomfort. Headache: Some users may experience headaches. Fluid Retention: Swelling of extremities.

Drug Interactions

Warfarin: May enhance the anticoagulant effect. Corticosteroids: Potential interaction, monitor for increased side effects.