Look for Drugs and Conditions

PRAMIPEXOLE

PRAMIPEXOLE

It is newer dopamine receptor agonist, selective for d2 receptors. It is absorbed orally with good bioavailability.

Indications

Parkinson's disease.


Dosage

0.125mg as starting dose, increase gradually till usual dose of 1.5-4.5mg/day.


Contra-Indications

Hypersensetivity, Pregnancy and lactation.


Special Precautions

Hepatic and Renal diseases.


Side Effects

Nausea, dizziness, hallucination, somnolence, confusion and orthostatic hypotension.


Drug Interactions

cyt p450 enzyme inhibitors inhibit metabolism and increase blood levels of pramipexole.


Ad 5