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R-Ondansetron is a medication belonging to the class of serotonin 5-HT3 receptor antagonists. It is primarily used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, or surgery. R-Ondansetron works by blocking the action of serotonin, a natural substance in the body that can trigger nausea and vomiting.


R-Ondansetron is indicated for the prevention and treatment of nausea and vomiting associated with chemotherapy, radiation therapy, and surgery. It is particularly effective in preventing nausea and vomiting in patients undergoing cancer treatment.


The dosage of R-Ondansetron varies depending on the patient's age, weight, and the specific condition being treated. It is usually taken orally, with or without food, as directed by a healthcare professional. In some cases, it may also be administered intravenously.


R-Ondansetron is contraindicated in individuals with a known hypersensitivity to ondansetron or any of the ingredients in the formulation. It should not be used in patients with severe liver impairment. Additionally, it should be used with caution in patients with certain heart conditions or electrolyte imbalances.

Special Precautions

Patients taking R-Ondansetron should be monitored for signs of serotonin syndrome, especially when used in combination with other serotonergic medications. It should be used cautiously in pregnant or breastfeeding women, as the safety of R-Ondansetron in these populations has not been established.

Side Effects

Common side effects of R-Ondansetron may include headache, constipation, diarrhea, dizziness, and fatigue. Rare but serious side effects may include allergic reactions, serotonin syndrome, and QT prolongation. Patients experiencing any adverse effects should seek medical attention promptly.

Drug Interactions

R-Ondansetron may interact with certain medications, including other serotonergic drugs, apomorphine, and medications that prolong the QT interval. It is important to inform the healthcare provider about all medications, supplements, and herbal products being taken to avoid potential interactions.

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