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Telithromycin

Telithromycin

It is a semi-synthetic erythromycin derivative and categorized as a ketolide.

Indications

It is indicated for the treatment of community acquired pneumonia caused due to susceptible bacteria for patients 18 years older and above.


Dosage

800 mg (2 tablets of 400mg) taken orally once every 24 hours, for 7-10 days. Can be taken with or without food.


Contra-Indications

It is contraindicated in cases of Myasthenia Gravis due to risk of fatal and life threatening Acute Respiratory Failure, It is also contraindicated in cases of hepatic dysfunction or hypersensitivity or Telithromycin or any of its constitutents. Pregnancy Category C medication- to be given to pregnant women only after justifying potential risk to the fetus.


Special Precautions

Hepatotoxicity, QTc prolongation, visual disturbances, loss of consciousness, Pseudomembranous colitis.


Side Effects

Diarrhoea, nausea, vomiting, headache, dizziness.


Drug Interactions

Concomitant administration with cisapride or pimozide is contraindicated. It is also contraindicated concomitantly with colchicine. Serious adverse reactions have also been reported with CYP3A4 inhibitors, Statins, Midazolam, and Calcium-channel Blockers metabolized by CYP3A4.


Other Brands With Same Generic
Brand Name Manufactured by
KETEK SANOFI AVENTIS PHARMA LTD.
Other Combination Brands
Brand Name Manufactured by
TELVI-R STADCHEM LIFESCIENCES
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