TIZANIDINE
It is centrally acting skeletal muscle relaxant; its major site of action is in the spinal cord .It preferentially inhibits polysynaptic mechanisms responsible for excessive muscle tone, mainly by reducing the release of excitatory amino acids from interneurons.It does not affect neuromuscular transmission.Painful muscle spasms.Spasticity.
Painful muscle spasm :2mg 3 times daily. Spasticity : daily dose should not exceed 6 mg.
Hypersensitivity.
Renal insufficiency,impaired liver function,driving vehicle or operating machinery. Pregnancy: Contraindicated. Lactation: Contraindicated. Elderly: Use with caution.
Drowsiness,fatigue,dizziness, dry mouth, nausea ,G.I disturbances.
Antihypertensives, including diuretics may cause hypotension and bradycardia
Brand Name | Manufactured by |
---|---|
MIELID MR | MITS HEALTHCARE |
SIRDALUD | NOVARTIS INDIA LTD |
TIZAN | Sun Pharmaceutical Industries Ltd. |
TIZAN SR | Sun Pharmaceutical Industries Ltd. |