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Filename: drivers/Session_files_driver.php
Line Number: 176
Backtrace:
File: /home/drugtodayonline/public_html/application/controllers/Drug_directory.php
Line: 9
Function: __construct
File: /home/drugtodayonline/public_html/index.php
Line: 311
Function: require_once
Severity: Warning
Message: session_start(): Failed to read session data: user (path: /var/cpanel/php/sessions/ea-php74)
Filename: Session/Session.php
Line Number: 143
Backtrace:
File: /home/drugtodayonline/public_html/application/controllers/Drug_directory.php
Line: 9
Function: __construct
File: /home/drugtodayonline/public_html/index.php
Line: 311
Function: require_once
Topotecan
Topotecan inhibits topoisomerase I, an enzyme involved in DNA replication.Metastatic carcinoma of the ovary after failure of initial or subsequent chemotherapy. Small cell lung cancer disease after failure of first line chemotherapy.
Before administration of topotecan, patient should have a baseline neutrophil count of > 1500 cells/mm3 and a platelet count of >100000 cell/mm3. The recommended starting dose is 1.5mg/m2 by IV infusion over 30 minutes daily for 5 consecutive days, starting on day 1 of a 21 day course. In absence of tumour progression a minimum of four courses are recommended, as tumour response may be delayed.
Known hypersensitivity to topotecan, patients with sever bone marrow depression.
Abdominal discomfort, intestinal obstruction,vomiting, diarrhoea, nausea, stomatitis, anorexia. Bone marrow suppression (primarily neutropenia, thrombo-cytopenia, anaemia.
Other antineoplastic agents : Myelosuppression may be more severe if topotecan is given with cisplatin. G-CSF : Coadministration of G-CSF and topotecan may prolong duration of neutropenia. If G-CSF has to be used, it should be started only on day 6 of the course i.e., 24 hr. after completion treatment with topotecan.
| Brand Name | Manufactured by |
|---|---|
| Admatop | ADMAC FORMULATIONS |
| Hycamtin | GLAXO-SMITHKLINE |
| Topocan | VENUS REMEDIES LIMITED |
| Topotec | UNITED BIOTECH |
| TOPOTEL | DABUR PHARMACEUTICALS LIMITED |
Severity: Warning
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Filename: mysqli/mysqli_driver.php
Line Number: 307
Backtrace:
File: /home/drugtodayonline/public_html/application/models/Site_ads_model.php
Line: 118
Function: query
File: /home/drugtodayonline/public_html/application/libraries/Common_lib.php
Line: 318
Function: get_front_ads_data
File: /home/drugtodayonline/public_html/application/views/front/salt_info.php
Line: 165
Function: common_footer_ads
File: /home/drugtodayonline/public_html/application/controllers/Drug_directory.php
Line: 331
Function: view
File: /home/drugtodayonline/public_html/application/controllers/Drug_directory.php
Line: 29
Function: drug_info
File: /home/drugtodayonline/public_html/index.php
Line: 311
Function: require_once
Severity: Warning
Message: Cannot modify header information - headers already sent by (output started at /home/drugtodayonline/public_html/system/core/Exceptions.php:271)
Filename: core/Common.php
Line Number: 570
Backtrace:
File: /home/drugtodayonline/public_html/application/models/Site_ads_model.php
Line: 118
Function: query
File: /home/drugtodayonline/public_html/application/libraries/Common_lib.php
Line: 318
Function: get_front_ads_data
File: /home/drugtodayonline/public_html/application/views/front/salt_info.php
Line: 165
Function: common_footer_ads
File: /home/drugtodayonline/public_html/application/controllers/Drug_directory.php
Line: 331
Function: view
File: /home/drugtodayonline/public_html/application/controllers/Drug_directory.php
Line: 29
Function: drug_info
File: /home/drugtodayonline/public_html/index.php
Line: 311
Function: require_once
Error Number: 1
Can't create/write to file '/tmp/#sql_3cd_0.MYI' (Errcode: 28 - No space left on device)
SELECT * FROM `dt_site_ads` WHERE `status` = '1' and `loc` = 'pre_footer_4' ORDER BY RAND() LIMIT 0,1
Filename: models/Site_ads_model.php
Line Number: 118