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Zaltoprofen

Zaltoprofen

Zaltoprofen, a preferential COX-2 inhibitor is a propinoic acid derivative, exhibited a potent inhibitor action on the nociceptive responses by blocking B-2 receptors.

Indications

For anti inflammatory and analgesic activity in rheumatoid arthritis, osteoarthritis, low back pain, periarthritis of shoulder, cervicobrachial syndrome, postoperative, post trauma, and post dental extraction.


Dosage

80-160 mg as and when required or thrice daily (not high doses).


Contra-Indications

Pregnancy, Active GI bleeding, Lactation.


Special Precautions

Asthma, bleeding disorders, cardiovascular disease, allergy due to aspirin.


Side Effects

Gastric discomfort/pain, nausea, photosensitivity (inflammation where sun hit), hypersensitivity such as rash/itch. Fatigue, loss of appetite, yellowing of the skin/eyes (liver dysfunction). Pain, pressured feeling in the pit of stomach, nausea, vomiting, blood vomiting, bloody stool (peptic ulcer, small/large intestine ulcer, hemorrahagic colitis). Fever, pain in throat, headache, nose or gum bleeding (agranulocytosis, thrombocytopenia).


Other Brands With Same Generic
Brand Name Manufactured by
ZALTO INTAS PHARMACEUTICALS LTD.
ZALTOKIN IPCA LABS LTD.
ZALTOP-80 ZYDAL PHARMACIA
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