Drug Safety Alert: DEG-Laced Cough Syrup Linked to Child Deaths in MP
The Drugs Testing Laboratory in Bhopal revealed that a cough syrup batch was contaminated with 46.28% diethylene glycol (DEG), prompting a global drug safety warning in reaction to unfounded reports of 14 child deaths in Madhya Pradesh's Chhindwara district. The tainted item, labelled Coldrif and manufactured by Sresan Pharmaceutical in Kancheepuram (Tamil Nadu), was discovered to contain dangerous quantities of DEG, a chemical solvent that can be lethal even in trace amounts.
A government analyst from the Food and Drugs Administration (FDA) in Madhya Pradesh confirmed that the syrup sample, which also had paracetamol, phenylephrine hydrochloride, and chlorpheniramine maleate, contained 46.28% diethylene glycol, much higher than the safe limit of 0.1% w/v, and this substance is "The sample was found adulterated with 46.28% w/v diethylene glycol, which is injurious to health," according to the report.
The findings come as public worry develops about the deaths of children allegedly caused by the consumption of the same sort of syrup. Madhya Pradesh Assembly Speaker Narendra Singh Tomar stated that the government had taken note of the matter and vowed strict action. "Those who have been found guilty will face repercussions. "There should be concern about the recurrence of similar situations," he stated.
Medical professionals warn that DEG contamination, as witnessed in previous international drug safety crises, can cause acute kidney failure, metabolic acidosis, convulsions, and coma, especially in children. In a widely circulated social media post, Hyderabad-based neurologist Dr Sudhir Kumar advised parents to avoid cough syrups altogether for minor viral illnesses. "Most children's coughs subside on their own. "Cough syrups do not cure or shorten illness, but they can be dangerous if contaminated," he told me.
Similar contamination findings have been reported in Tamil Nadu, raising worries about a wider supply chain risk. Regulatory inspectors are believed to be investigating the origin of raw ingredients as well as the distribution route of the affected batch.
According to public health specialists, this experience emphasises the significance of rigorous pharmacovigilance, independent lab audits, and stronger recall mechanisms in protecting the public from tainted formulations. The drug safety alert has reignited debate over India's quality surveillance systems and the crucial need to upgrade testing facilities at the state and national levels.
Meanwhile, the Central Drugs Standard Control Organisation (CDSCO) has initiated an inquiry into any interstate violations, and health officials have recommended parents report any bad symptoms in children who have taken the syrup, such as vomiting, disorientation, or decreased urine.
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