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Roxatidine Acetate Hydrochloride- Side Effects, Uses and Precautions

Look for Drugs and Conditions

ROXATIDINE ACETATE HYDROCHLORIDE

ROXATIDINE ACETATE HYDROCHLORIDE

It is a potent and selective H2-receptor antagonist useful in treatment of acid peptic disorders. It markedly inhibits basal, as well as stimulated gastric acid secretion in a dose dependent fashion. Roxatidine has no antiandrogenic activity: no sinificant effect on hypothalamic-pituitary-gonadal or adrenal axis. Intake of food or antacids has no effect on the absorption of Roxatidine and has no adverse drug interacting with benzodiazepines antihypertensives.

Indications

Duodenal and benign gastric ulcers and reflux oesophagitis. Prophylaxis or recurrent gastric/duodenal ulcers and as maintenance therapy.


Dosage

150 mg once daily in the evenin or 75 mg twice daily for 4-6 wks. Maintenance therapy; 75 mg daily in the evening.


Contra-Indications

VHypersensitivity, malignant gastric ulcers, or anuria.


Special Precautions

In severe hepatic & renal impairment dose must be reduced. Paediatrics: Not recommended in children under14. Pregnancy: Should not be used. Lactation: Should not be used. Elderly: Reduce the dose.


Side Effects

Occasional headache, gastro-intestinal disturbances, rarely dizziness, seep disturbances, restlessness and drowsiness, visual disturbances pain in muscles and joints, hypersensitivity reactions. Transient impairment of sexual drive.


Drug Interactions

None known.


Other Brands With Same Generic
Brand Name Manufactured by
ROTANE AVENTIS PASTEUR
ZORPEX STANCARE

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