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Aceclofenac in Beta Cyclodextrin with Paracetamol

Aceclofenac in Beta Cyclodextrin with Paracetamol

Aceclofenac in Beta Cyclodextrin with Paracetamol is a pharmaceutical formulation that combines the anti-inflammatory properties of aceclofenac with the analgesic and antipyretic effects of paracetamol, both of which are encapsulated within beta-cyclodextrin for enhanced solubility and bioavailability.


This combination medication is primarily indicated for the relief of pain and inflammation associated with various conditions, such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and musculoskeletal disorders. It is also effective in managing fever.


The dosage may vary depending on the patient's age, weight, and the severity of the condition. However, a typical adult dose may involve one tablet taken orally, usually twice a day after meals. It is essential to follow the prescribed dosage and instructions provided by a healthcare professional.


This medication is contraindicated in individuals with a known hypersensitivity to aceclofenac, paracetamol, or beta-cyclodextrin. It is also not recommended for patients with a history of gastrointestinal bleeding, severe hepatic impairment, or renal dysfunction.

Special Precautions

-Caution is advised in patients with a history of peptic ulcer, hypertension, heart failure, or asthma. -Monitoring of renal and hepatic function is recommended during prolonged use. -Avoid alcohol consumption during the course of treatment. -Elderly patients may be more susceptible to adverse effects; therefore, careful monitoring is necessary.

Side Effects

Common side effects may include nausea, dyspepsia, headache, and dizziness. Gastrointestinal disturbances such as abdominal pain and diarrhea may also occur. In rare cases, severe skin reactions and blood disorders have been reported. If any adverse reactions occur, medical attention should be sought.

Drug Interactions

This medication may interact with certain drugs, including anticoagulants, diuretics, lithium, and methotrexate. Concurrent use with other NSAIDs should be avoided to prevent an increased risk of adverse effects. It is essential to inform the healthcare provider about all medications being taken.

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