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-Alprazolam with Propranolol is a combination of medications used to treat certain conditions. Alprazolam is a benzodiazepine that affects the central nervous system, while Propranolol is a beta-blocker that acts on the cardiovascular system. -This drug combination is a potent anxiolytic drug, used to treat anxiety and panic disorder. Alprazolam belongs to the class of medication known as benzodiazepine and acts as a tranquilliser on the central nervous system. Propranolol is a potent beta blocker, used to treat heart disorders, anxiety, and migraine.


-Anxiety Disorders: Alprazolam is indicated for the short-term relief of symptoms of anxiety disorders. -Panic Disorders: Alprazolam may be used in the management of panic disorder. -Performance Anxiety: Propranolol is sometimes used to alleviate symptoms of performance anxiety, such as tremors and rapid heartbeat.


Dosage is individualized based on the specific condition, severity, and patient response. It is crucial to follow the prescribed regimen provided by the healthcare professional.


-Hypersensitivity: Avoid in patients with known hypersensitivity to alprazolam, propranolol, or related components. -Cardiogenic Shock: Propranolol is contraindicated in cardiogenic shock.

Special Precautions

-Respiratory Conditions: Caution in patients with respiratory conditions, as benzodiazepines can depress respiratory function. -Cardiovascular Disorders: Propranolol should be used with caution in patients with pre-existing cardiovascular conditions. -Consult a physician before using it during pregnancy and breastfeeding.

Side Effects

-Common side effects may include drowsiness, dizziness, and changes in heart rate. Serious side effects may include respiratory depression (with high doses of alprazolam) or worsening of heart failure (with propranolol). -Dizziness, depression, dry mouth, muscle weakness, slow heart rate, memory impairment, and confusion.

Drug Interactions

-Central Nervous System Depressants: Increased risk of sedation and respiratory depression when alprazolam is combined with other CNS depressants. -Antihypertensive Drugs: Enhanced antihypertensive effects when propranolol is used with other antihypertensive medications. -Warfarin, Aspirin, Diclofenac, Amitriptyline, coumadin, ketoconazole, Prednisone, Indomethacin.

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