Advanced breast cancer in postmenopausal women.
1mg once daily. Advanced disease: continue until tumor progression.
Pregnancy and lactation; moderate or severe hepatic disease/renal impairment; premenopausal women.
Estrogen containing therapies should not be used with anastrozole as they may diminish its pharmacological action.Tamoxifen should not be co-administered with anastrozole.
Hot flushes, vaginal dryness, vaginal bleeding, hair thinning, anorexia, nausea, vomiting, diarrhoea, headache, arthralgia, bone fractures, rash (including Stevens-Johnson syndrome). Asthenia and drowsiness may initially affect ability to drive or operate machinery.
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