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It is a relatively cardio selective b-andrenoceptor blocking agent without membrane stabilizing or intrinsic sympathomimetic activities. Following oral doses of 50 or 100 mg, both b-blocking and antihypertensive effects persists for at least 24 hrs. because of higher lipid solubility.


Hypertension, angina pectoris, myocardial infarction.


Adults: 50-100 mg daily. Children:1-1.3mg/kg/day daily or two divided doses.


Sinus bradycardia, heart block greater than first degree, cardiogenic shock, overt cardiac failure, anuria or known hypersensitivity reaction to atenolol and/or nifedipine (In case of combinations).

Special Precautions

Renal impairment, pregnancy, diabetes, untreated cardiac failure, sudden withdrawal may exacerbate angina pectoris & may precipitate M.I. Anaesthetic agents may further cause depression of myocardium. Myocardial contractility. Paediatrics: Not recommended. Pregnancy: No risk factor. Lactation: Present in breast milk. Elderly: No special problem.

Side Effects

Bradycardia, cold extremities, leg pain, dizziness, tiredness, fatigue & lethargy, skin rashes and/or dry eyes.

Drug Interactions

With verapamil precipitation of heart failure.Simultaneous withdrawl of Atenolol & Clonidine result in rebound hypertension. Indomethacin reduces antihypertensive effect.

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