Cinnarizine with Domperidone

Cinnarizine with Domperidone is a combination medication that includes Cinnarizine, an antihistamine with antiemetic properties, and Domperidone, a prokinetic agent. This combination is often used to relieve symptoms associated with vertigo, motion sickness, and nausea.

Indications

-Vertigo: Used to alleviate symptoms of vertigo and dizziness. -Motion Sickness: Effective in preventing and treating motion sickness. -Nausea and Vomiting: Domperidone component is added for the relief of nausea and vomiting.

Dosage

Dosage may vary based on the specific condition and individual patient factors. Typically, the medication is administered orally.

Contra-Indications

-Hypersensitivity: Avoid in patients with known hypersensitivity to cinnarizine, domperidone, or related components. -Prolactinoma: Contraindicated in patients with prolactin-secreting pituitary tumors.

Special Precautions

-Liver Dysfunction: Use with caution in patients with liver impairment, as domperidone is metabolized in the liver. -Cardiac Issues: Evaluate cardiovascular status before prescribing, especially in patients with pre-existing cardiac conditions.

Side Effects

Common side effects may include drowsiness, dry mouth, and gastrointestinal disturbances. Serious side effects are rare but may include extrapyramidal reactions with high doses of domperidone.

Drug Interactions

-Antifungal Agents: Some antifungal drugs may interact with cinnarizine. -QT Prolonging Drugs: Caution is advised when combining with drugs that may prolong the QT interval.