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Desloratadine

Desloratadine

It is a new, selective peripheral histamine H1-receptor antagonist with more potent antiallergenic properties than loratadine itself. It also exhibits anti-inflammatory activity which is mediated by inhibiting the release of proinflammatory mediators from human mast cells/basophils.

Indications

Seasonal allergic rhinitis, chronic idiophathic urticaria.


Dosage

Adults: 5mg once daily.


Contra-Indications

Hypersensitivity, pregnant and lactating females.


Special Precautions

Renal impairment, alcoholic beverages, ability to drive or use machinery, caution is warranted.


Side Effects

Headache, dry mouth and fatigue.


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