HAEMOPHILUS b CONJUGATE VACCINE

Haemophilus influenzae vaccine is used for active immunisation against Haemophilus influenzae type b infections, which are one of the major causes of meningitis and other severe systemic infections in young children. It is prepared from the highly purified capsular polysaccharide antigen of Haemophilus influenzae type b covalently conjugated with purified Tetanus toxoid protein. It is available in freeze dried form and therefore is highly stable. It induces stong immune response is 95-100% vaccinees with least reactogenicity.

Indications

Immunisation of children from 2-71 months of age against invasive diseases caused by Haemophilus influenzae type b (meningitis, septicaemia cellulitis, arthritis, epiglotitis.

Dosage

The vaccine can be given concurrently with other paediatric vaccines like OPV, MMR etc. but at different sites. Recommended schedule of dosage is given in tabular form.

Contra-Indications

Hypersensitivity to constituents of the vaccine, including to diptheria toxoid.

Special Precautions

Epinephrine (1:1000) should be available, caution should be exercised in patients with congulation disorders, acute febrile illnessess and immunosuppressed patients where the vaccine may not be effective.

Side Effects

Mild and transient, local erythema, swelling, fever, irritability, sleepiness, GIT distribances, rashes & anorexia.