Look for Drugs and Conditions

Lomustine (Nitrosoureas)

Lomustine (Nitrosoureas)

It is highly lipid soluble alkylating agent with a wide range of antitumour activity. They cross blood brain barrier and are effective in meningeal leukemias & brain tumours.

Indications

Meninigeal leukemias, brain tumours, Hodgkin's disease.


Dosage

100-130mg/sqm body surface area single oral dose every 6 wks.


Contra-Indications

Pregnancy, lactation, Hypersensitivity.


Special Precautions

Renal impairment. C.N.S disturbances, Monitor blood counts. Paediatrics: Not recommended in infants. Pregnancy : Safety not established. Lactation : Safety not established. Elderly : Use with caution.


Side Effects

Nausea, vomiting, seizures, Bone marrow depression is delayed for 6 wks. Visceral fibrosis and renal damage.


Drug Interactions

Theophylline cause leucopenia and thrombocytopenia.


Other Brands With Same Generic
Brand Name Manufactured by
Lomat NEON LABORATORIES LTD.
Lustine SAMARTH LIFE SCIENCES PVT LTD
MOOSTIN MIRACALUS PHARMA PVT. LTD.
Ad 5