Look for Drugs and Conditions

METHYL PREDNISOLONE SODIUM SUCCINATE

METHYL PREDNISOLONE SODIUM SUCCINATE

It has anti-inflammatory potency than hydrocortisone. It has a faster onset of action than Dexamethasone. It offers significant improvement in air-flow parameters like FVC & FEV1.It potentiates the action of Bronchodilators. Its use in emergency treatment of severe asthma can prevent significant morbidity. Methylprednisolone sodium succinate is a corticosteroid medication used to treat various conditions by reducing inflammation and suppressing the immune system. Methylprednisolone sodium succinate is a synthetic glucocorticoid, belonging to the corticosteroid class of drugs. It is available as a sterile white powder for intravenous or intramuscular administration after reconstitution.

Indications

-Inflammatory Conditions: Methylprednisolone sodium succinate is used to manage inflammation associated with various conditions, such as rheumatoid arthritis, osteoarthritis, and dermatologic disorders. -Allergic Reactions: It is prescribed for allergic and hypersensitivity reactions. -Respiratory Disorders: Treatment of severe asthma and chronic obstructive pulmonary disease (COPD). -Autoimmune Disorders: Used in autoimmune diseases like lupus and multiple sclerosis. -Organ Transplants: To prevent rejection after organ transplantation. -Severe Allergic Reactions: It can be administered in emergency situations for severe allergic reactions. -Allergic states, Respiratory diseases, Rheumatic disorders, Endocrine disorders, Collagen disease, Dermatologic diseases, Ophthalmic diseases, Haematologic disorders,Neoplastic disease, Oedematous states, Nervous system, Cardiovascular conditions, Organ Transplantation, Prevention of nausea and vomiting associated with cancer chemotherapy.


Dosage

-Dosage depends on the specific condition being treated, patient's age, weight, and overall health. It is usually administered as an injection under the supervision of a healthcare professional. -30mg per kg (IV) over a peroid of at least 30 min.,may be repeated every 4-6 hours up to 48 hours. Rheumatic disorders: 1 gm/day for 3-4 days(IV). Multiple sclerosis : 1 gm/day for 3 days(IV) or 1gm/day for 5 days(IV).


Contra-Indications

-Systemic Fungal Infections: Patients with systemic fungal infections should avoid methylprednisolone sodium succinate. -Hypersensitivity: Individuals with known hypersensitivity to corticosteroids should not use this medication. -Live Vaccines: Contraindicated in patients receiving live vaccines. -Systemic fungal infections. Known hypersensitivity to components.


Special Precautions

-Diabetes: Use with caution in patients with diabetes, as corticosteroids can elevate blood glucose levels. -Cardiovascular Disease: Caution is advised in individuals with a history of cardiovascular disease. -Infections: Increased susceptibility to infections; monitor for signs of infection during therapy. -Osteoporosis: Long-term use may lead to bone loss; consider calcium and vitamin D supplementation.


Side Effects

-Common side effects may include insomnia, increased appetite, weight gain, and fluid retention. Serious side effects include gastrointestinal bleeding, increased risk of infection, and adrenal suppression. -Aseptic necrosis of femoral and humeral heads, Peptic ulcer, Nausea, Vomiting and a bad taste in the mouth.


Drug Interactions

-Anticoagulants: Increased risk of bleeding with anticoagulant drugs. -Diuretics: Enhanced potassium loss with diuretic use. -Insulin and Oral Hypoglycemics: May require adjustment of diabetes medications. -Vaccines: Reduced efficacy of live vaccines; avoid live vaccines during treatment.


Other Brands With Same Generic
Brand Name Manufactured by
AMBSONE AMBLE BIOTECH
ARPRED I. I. F. A. HEALTH CARE
ASPRED AMERICAN REMEDIES
B-CORT M BLAZON BIOTEK
BITOCORT M SOMSA PHARMACEUTICALS
CIMSOLON BIOCARE (Div. of Health biotech Ltd.)
CIMSOLON HEALTH BIOTECH LTD.
CORSOL CORAL PHARMA
CORTYPAN PANM LABS (INDIA)
DEESOLONE PARAGON PHARMACEUTICALS
DELZ forman medics pvt. ltd.
DEPOREST INJ BAXY PHARMACEUTICALS
DEPOTEX GERMAN REMEDIES LTD.
DGLON ENRICO PHARMACEUTICALS
DORALON ORGANIC NOVA PHARMA
DRUDROL DRUKST BIOTECH
DUCOMETH AUREL BIOLIFE
EDIPRED SCOTT-EDIL PHARMACIA LTD.
EDNIWEL EMMWELL PHARMACEUTICALS PVT LTD
EMPRED-4 ACCENTUS HEALTHCARE
EPRED-4 ELIXIRIO PHARMACEUTICALS PVT. LTD.
FAMETH FANTABULOUS PHARMA
FIGOPRED MONARK BIOCARE
FINEBOND TRAUMAFINE PHARMACEUTICALS
FYPRED PHYTOCHEM HEALTHCARE PHARMACEUTICALS
GEMDROL GENETIC PHARMA
GEXIPRED INCEPTA Division Of Aster Medipharm Pvt. Ltd
GIALON-4 ANGIA RX DRUG FORMULATION
GLUDROL GLOBATE PHARMA
GMP GRAMPUS LABORATORIES
HAPPISONE MISSION HAPPINESS DIVINE PVT LTD
HOXAPRED M HOCHEST BIOTECH
IVEPRED Sun Pharmaceutical Industries Ltd.
JASCORT JASCO LAB PVT. LTD.
JMPRED FOREX PHARMACEUTICAL
LEXTROID-4 LEXUS (INDIA) ORGANICS
LITCORT M LITMUS PHARMA
M-PROUD TALENT HEALTHCARE
M-SOL KAVYA HEALTHCARE
MAMA LEO FORMULATIONS (P) LTD.
MECONEZ-PD SITNEZ BIOCARE PVT. LTD.
MEDAY CANBRO HEALTHCARE
MEDEL AXYZEN LIFE SCIENCES
MEGACORT AINGO PHARMA
MEGPREG-4 Regency Healthcare
MEP ZEN LABS
MEP SOLU ZEN LABS
MEPLOR LORETTA BIOTECH
MEPPY ANT PHARMACEUTICALS PRIVATE LIMITED
MEPRYCA Aryca Pharmaceuticals
MEPRYCA-16 Aryca Pharmaceuticals
MEPRYCA-4 Aryca Pharmaceuticals
MEPRYCA-8 Aryca Pharmaceuticals
MEPSOLON ARCHICARE
MERISON IRIS BIOSCIENCES
METCORT AUZTUS LABORATORIES PVT. LTD.
METHYDNICARE AB ALLCARE BIOTECH
METHYPRED HECURES (ULTRA HEALTHCARE)
METLONE DR. DERMA EXPERT SKIN CARE & CURE
METLONE ZORION DRUGS & HERBS PVT.LTD
METPRED NEXGEN LIFE SCIENCES
METROZ-4 OCTAVIUS GROUP OF COMPANIES
METSOL KAVYA HEALTHCARE
METSOLONE METAMORF LIFESCIENCES
MILPRIDE HAMSWELL LIFECARE
MOST CAPITAL PHARMA
MP-SOL SOLARIUM HEALTHCARE
MPD JOHNLEE PHARMACEUTICALS PVT LTD
MPD JOHNLEE PHARMACEUTICALS PVT LTD
MPD-4 MARGAVE PHARMACEUTICALS
MPGEN SIGNA
MPRED PINARC LIFE SCIENCES
MPROZ-A ROUZEL PHARMA
MYPRED INDOSS LIFE SCIENCES
MYSOLE MARTYN NIKK PHARMA PRIVATE LIMITED
NEOMEDVCB VCB LIFE SCIENCES PVT. LTD.
NEXPRED NEXKEM PHARMACEUTICALS
NEXPRED-A NEXKEM PHARMACEUTICALS
NIMSLON NIMBLES BIOTECH
NIXPRED SAPHNYX LIFE SCIENCES
NIXPRED TANSY MOLEQULE
NU-PRED SARAN BIOTECH
PDSOLONE SWISS PARENTERALS
PREBIEN SWISS PARENTERALS
PREDA-MET AAA PHARMACEUTICALS PVT. LTD.
PREDFAST AVONIC LIFE SCIENCES
PREDISA-16 STADCHEM LIFESCIENCES
PREDISA-4 STADCHEM LIFESCIENCES
PREDMAX-4 AMWIN PHARMA PVT LTD
PREDMIGIT LEGITIMED HEALTHCARE Pvt Ltd
PREDMUS Naira Derma (Div. of Dhamus Pharma)
PREDMUS Dhamus Pharma
PREDNOSIS GNOSIS PHARMACEUTICALS PVT. LTD.
PREDORG MEDCURE ORGANICS
PREDOSS MEDILIFE HEALTH SCIENCES PVT.LTD
PREDUS GLOBUS REMEDIES LTD.
PREMETH APOTEX LIFE SCIENCES
PRESLON M KENTRECK LABORATORIES PVT. LTD
PRIDROL-8 PRIDE HEALTHCARE
QUPRED QUIXOTIC PHARMA (P) LTD.
RACORT 4 SSR BIOTECH
RANIPRED RANIZ INTERNATIONAL
RESLONE M RESEARCH MEDICINES PVT.LTD
ROLMET-4 ONE PHARMA DRUGS & PHARMACEUTICALS
ROPRED RONISH BIOCEUTICALS
ROPRED 40 RONISH BIOCEUTICALS
SCOPRED TYSCON PHARMA
SIXAD-4 DT LIFECOM PRIMA (INDIA) PVT. LTD.
SOLAN-40 DR. ETHIX's
SOLME BLUBELL PHARMA
SOLULIFE HUMAN LIFE SCIENCES
SYM-4 ARLAK BIOTECH PVT. LTD.
TIKPRED GRACIA LIFE SCIENCES INDIA PVT. LTD.
TROPY ALTAR PHARMA
TRUPED-M TRUE CARE PHARMACEUTICALS
ULTRAPRED ULTRA CHIRON PHARMA
VELPRED CALIBER HEALTHCARE
ZENMP ZENMARK HEALTHCARE
ZOPRIDE Zodley Pharmaceuticals Pvt. Ltd.
ZORED ZODAK HEALTHCARE
Ad 5