Miglitol
Miglitol is a alpha glucosidase inhibitor similar in action to acarbose.In the management of type 2 diabetes mellitus alone or with a sulfonylurea.
Usual initial doses are 25mg three times daily with meals, increased if necessary to max of 100mg three time daily.
Hypersensitivity, renal clearance r the presence of inflammatory bowel disease, diabetic ketoacidosis,colonic ulceration, or partial intestinal obstruction.
Hypoglycaemia.
Adverse reactions:Abdominal pain, diarrhea, flatulence, skin rash.
Miglitol may significantly reduce the bioavailability of ranitidine and propranolol. Intestinal adsorbents (e.g., charcoal) and digestive enzyme preparations containing carbohydrate splitting enzymes (e.g., amylase, pancreatin) may reduce the effect and should not be taken concomitantly.
