MOXIFLOXACIN
The bactericidal action of moxifloxacin results from the interference with topoisomerase II and IV (DNA gyrase). Topoisomerases are essential enzymes that control DNA topology and assist in DNA replication, repair and transcription. It is effective against b-lactam and macrolide resistant bacteria.Treatment of acute Bacterial Sinusitis Acute Bacterial Exacerbation of Chronic Bronchitis and Community Acquired Pneumonia in adult patients (18 years of age and above).
400mg tablet taken orally every 24 hours.
Hypersensitivity.
Quinolones may cause CNS events including nervousness, agitation, insomnia, anxiety, nightmares or paranoia, pregnancy women. The safety and effectivness of moxifloxacin in pediatric patients, adolescents (less than 18 years of age), pregnant women and lactating women have not been established.It should be used with caution when given concurrently with cisapride, erythromycin, antipsychotics, and tricyclic antidepressants drugs.It should be used with caution in patients with ongoing proarr
Nausea, diarrhea, headache, vomiting, dizziness, nervousness, agitation, nightmares.
Antacids, sucralfate, didanosine, multivitamins, and iron, zinc, or magnesium supplements. You should take moxifloxacin at least 4 hours before taking these drugs or 8 hours after taking these drugs.
