Ofloxacin with Metronidazole

Ofloxacin with Metronidazole is a combination medication that contains two active ingredients: Ofloxacin, a fluoroquinolone antibiotic, and Metronidazole, an antiprotozoal and antibacterial agent. Below is detailed information about this combination: Ofloxacin is a synthetic broad-spectrum antibiotic that belongs to the fluoroquinolone class. It works by inhibiting the enzymes involved in DNA replication, thereby preventing bacterial growth. Metronidazole, on the other hand, is an antibiotic that is effective against certain bacteria and parasites. It works by disrupting the DNA structure of microorganisms, leading to their death.

Indications

This combination is commonly prescribed for the treatment of various infections, including but not limited to: -Respiratory tract infections -Urinary tract infections -Gastrointestinal infections -Skin and soft tissue infections -Pelvic inflammatory disease -Bacterial vaginosis -Intra-abdominal infections

Dosage

The dosage may vary depending on the specific infection and the patient's medical condition. It is essential to follow the prescribed dosage and duration as instructed by the healthcare provider.

Contra-Indications

This combination is contraindicated in individuals with a known hypersensitivity to Ofloxacin, Metronidazole, or any other components of the medication. It is also not recommended during pregnancy, especially in the first trimester, unless the potential benefits outweigh the risks.

Special Precautions

Caution is advised in patients with a history of epilepsy, neurological disorders, or blood disorders. It is essential to inform the healthcare provider about any existing medical conditions or medications being taken, including herbal supplements.

Side Effects

Common side effects may include nausea, vomiting, diarrhea, dizziness, and headache. Serious side effects such as tendonitis, peripheral neuropathy, and allergic reactions are rare but possible. If any unusual or severe side effects occur, medical attention should be sought promptly.

Drug Interactions

Ofloxacin with Metronidazole may interact with certain medications, including anticoagulants, cyclosporine, and some antacids. It is crucial to inform the healthcare provider about all medications being taken to avoid potential interactions.