Tapentadol hcl

Indications

Moderate to severe acute pain.

Dosage

Oral, 50-100mg 4-6 hourly.

Contra-Indications

MAO inhibitors, asthma, respiratory depression, paralytic ileus.

Special Precautions

Cause CNS depression so use carefully in drivers and machine operators, may cause billiary spasm, avoid CNS depressant along with it, chance of Dependence and abuse, head injury. Pregnancy: Category C. Not to be used during labor it can cause respiratory depression in newborn. Lactation : Not recommended. Children : Safety and efficacy not established. Ederly : Use with lower dose.

Side Effects

Nausea, dizziness, vomiting, somnolence, constipation, pruritus, dry mouth, hyperhydrosis, fatigue.

Drug Interactions

MAO Inhibitors, triptans, SSRIs, SNRIs, TCAs, alcoho