Tenofovir

Indications

In combination with other antiretroviral agents for the treatment of HIV-1 infection.

Dosage

Adults : 300mg once daily. >50 : 300mg/day, 30-49 : 300mg every 48 hours, 10-29 : 300mg twice a week.

Contra-Indications

Hypersensitivity.

Special Precautions

Should not be used in combination with the fixed-dose combination product, since it is a component of that product.

Side Effects

Pain, fever, abdominal pain, back pain, asthenia, nausea, dyspepsia, vomiting, musculoskeletal arthralgia, myalgia, insomnia, dizziness, anxiety, skin and appendages rash event.

Drug Interactions

Tenofovir is generally a well tolerated medication with a low pill burden and demonstrates potent antiretroviral activity. These characteristics have led to its widespread use in clinical practice.