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Tofisopam

Tofisopam

Tofisopam is an atypical benzodiazepine, structurally related to 1,4-benzodiazepines. It possesses anxiolytic properties, but unlike other benzodiazepines, it is not sedative, or anticonvulsant, or muscle relaxant and has little effect on motor skills and low amnesic properties. Tofisopam is a benzodiazepine derivative with anxiolytic (anti-anxiety) properties. It belongs to the class of psychoactive drugs and is primarily used for the management of anxiety disorders.

Indications

-Tofisopam is indicated for the treatment of generalized anxiety disorder and other conditions characterized by excessive and persistent worry or anxiety.


Dosage

-The typical dosage of tofisopam varies depending on the individual's age, medical condition, and response to treatment. It is usually administered orally, and the recommended dose should be determined by a healthcare professional. -oral; 50-300mg per day in three divided doses


Contra-Indications

Tofisopam is contraindicated in individuals with a known hypersensitivity to the drug or any of its components. It should be avoided in patients with severe respiratory insufficiency, sleep apnea, and acute narrow-angle glaucoma.


Special Precautions

-Caution is advised in patients with a history of substance abuse or dependence. -Tofisopam should be used with caution in elderly patients and those with impaired hepatic or renal function. -Avoid alcohol consumption during treatment, as it may enhance the sedative effects of tofisopam. -Sleep disturbance may occur Paediatric: Data not sufficient Pregnancy: Not recommended Lactation: Data not sufficient Elderly: Data not sufficient


Side Effects

-Common side effects may include drowsiness, dizziness, headache, and gastrointestinal disturbances. Less frequently, allergic reactions or paradoxical reactions such as increased anxiety may occur. If any side effects persist or worsen, it is important to seek medical attention. -Temporary gastrointestinal complaints, itching and exanthema


Drug Interactions

Tofisopam may interact with other central nervous system depressants, including alcohol, sedatives, and antipsychotic medications. Inform your healthcare provider about all the drugs you are currently taking to prevent potential interactions.


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