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Trifluoperazine is an antipsychotic medication used to treat various mental health conditions, including schizophrenia and anxiety disorders. It works by affecting certain neurotransmitters in the brain, helping to alleviate symptoms such as hallucinations, delusions, and agitation.


Trifluoperazine is indicated for the treatment of schizophrenia, as well as for managing severe anxiety and agitation associated with certain psychiatric disorders.


-Dosage of trifluoperazine varies depending on the condition being treated, the patient's age, and other individual factors. It is typically administered orally in tablet form, with dosages adjusted gradually to achieve optimal therapeutic effects. -1-2 mg twice daily.


Drowsines, coma, extrapyramidal reactions, hepatic/renal disease, hypersensitivity.

Special Precautions

Epilepsy, G.I. obstruction, CVD, phaeochromocytoma, brain damage. Avoid prolonged use. Paediatrics: Not recommended below 6 years. Pregnancy & LactationUse with caution only if clearly indicated. Elderly: Use only if clearly indicated.

Side Effects

Common side effects of trifluoperazine may include drowsiness, dizziness, dry mouth, constipation, and blurred vision. More serious side effects such as tardive dyskinesia and neuroleptic malignant syndrome are rare but can occur, particularly with long-term use or high doses.

Drug Interactions

Potntiate CNS depressants. MAOIs results in orthostatic hypotension. Guanethidine, methyldopa, clonidine reverses antihypertensive effects. Antacids decreases trifluoperazine bioavailability.

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