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Study Finds No Significant Difference Between Fasting and Regular Caloric Restriction for Weight Loss

A recent head-to-head trial comparing fasting diets with regular caloric restriction has yielded surprising results: there was no significant difference in weight loss or other health indicators between the two groups. The study, led by Dr. Nisa Maruthur and her team at Johns Hopkins Medicine, challenges the notion that intermittent fasting is superior for weight loss.


Presented at the annual meeting of the American College of Physicians and published in the Annals of Internal Medicine, the study involved 41 obese individuals with pre-diabetes. Participants were divided into two groups: one followed a time-restricted eating pattern, consuming calories only between 8 a.m. and 6 p.m., while the other group ate within a more conventional timeframe from 8 a.m. to midnight.

Surprisingly, both groups were provided with identical meals containing the same calorie content and macronutrient composition. After 12 weeks, researchers found no significant difference in weight loss between the two groups. Both groups experienced a similar reduction in body weight, with participants on the fasting regimen losing an average of just over 5 pounds, slightly less than the 5.7 pounds lost by those on the regular eating schedule.

Moreover, there was no significant disparity in blood sugar changes between the groups, indicating that fasting did not confer additional metabolic benefits compared to traditional caloric restriction.

In light of these findings, the researchers concluded that obese individuals with pre-diabetes may achieve comparable weight loss outcomes by simply reducing their daily caloric intake, irrespective of their eating schedule.

In an accompanying editorial, nutrition researchers Drs. Krista Varady and Vanessa Oddo from the University of Illinois praised the study for its rigorous design. They acknowledged that while time-restricted eating has gained popularity due to its simplicity and avoidance of calorie counting, the study underscores the effectiveness of fasting primarily because it naturally reduces calorie intake.

Despite the study's findings, Varady and Oddo noted that fasting diets may still hold appeal for individuals who find it cumbersome to track calories daily. By simplifying the approach to weight loss, fasting diets offer a viable alternative for those seeking effective and straightforward interventions for obesity management.

In summary, while time-restricted eating may not offer distinct advantages over traditional caloric restriction for weight loss, it presents a simplified approach that resonates with many individuals striving to address obesity without the need for meticulous calorie counting.



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